CVS (a pharmacy and everything else type of store) will clear their shelves of tobacco products this year, by October 1. Even though they will take a hit in profits (like $2 billion), it's gotten to the point where "the regulatory issues and costs exceed the benefit (of selling tobacco)."
Some Target stores have given up on selling tobacco as well, because it's too difficult to police sales.
Also, Walgreens (another pharmacy/everything else store) is "evaluating whether to continue carrying tobacco products in it more than 8,600 stores."
Taxes have gone up significantly here in the U.S. on cigarettes, and the consensus may be that more Americans will not take up smoking, or they will quit.
*Quotes are from Crain's Chicago Business magazine.