MTHFR may be a reason some people don't do well on a vegan diet. If you search "vegan MTHFR" you can find discussions about it being a problem. I have MTHFR and my experience is that it is a problem. I'm posting this for help and I'm sure that I'm missing information but I feel that I can't process supplement b12. My blood test shows 950 but I still have deficiency symptoms so after almost three years as a vegan I ate salmon and the next day the symptoms were gone. It was like waking up from a sleep. Now I eat vegan and when I start to feel poor I eat salmon. This is not a joke. I have tried many forms of supplements, tabs, sub lingual and injections and they don't work like eating salmon. I don't want to eat fish I want a supplement that works. Any big brains on the subject reading this? Thanks for reading.
Scott, I also have the MTHFR genetic mutation and have read similar things as you have, that people with this mutation have a hard time detoxing and that we struggle to methylate B vitamins anyway. I am super sensitive to anything artificial and struggle to take most, if not all, supplements. Anytime I take them, I get a burning sensation all over my body. I started out as a raw vegan back in April 2013. Several of my symptoms did improve, but there are several that got worse. I added back cooked starch after approximately one year. I have always been slim, but adding back cooked food caused me to gain excessive weight rather quickly.
Like I said, I have read many articles that say people with MTHFR cannot thrive on a vegan diet, especially not raw. But, then I read SO MANY testimonials of people overcoming MS, lupus, diabetes, heart disease, etc and it is known that MTHFR affects over 30% of the population and they are thinking the percentage is even higher than that.
I struggle with knowing what to do. I reached out and asked for guidance on here about MTHFR and I was basically told that epigenetics are more important, and this is what controls how our genes express themselves.
My integrative doctor wants me to do further genetic blood tests because she thinks I have another SNP further down the methylation cycle, I think it is the COMT gene. If this one is mutated, she says there are other precautions I need to take to further improve my health. It is scary because I am still challenged with some of the same symptoms I had when I came to 30BAD.
Many people do not believe in the genetic disposition and think the MTHFR is just another 'bandwagon' doctors are jumping on. I think it is legitimate and struggle because I want to do the best thing for my health, so I can live a long healthy life.
I know this mutation is responsible for a lot of heart-related health issues, as well as cancer. I have lost several family members to heart attacks, and most were at the early ages of 46-49. It is truly scary.